Antibiotic Resistance Pattern and Plasmid Curing of Escherichia coli Isolated from Soil Samples in Girei, Nigeria

In this study, seventy five (75) soil samples were collected from farmlands, riverbanks and dumpsites screened for the presence of Escherichia coli via inoculation on EMB, Gram’s staining some biochemical tests. Overall, 15 E. isolates identified. Dumpsite has highest number with 9(60%), followed by farmland four 4(26.7%) isolates, lastly riverbank two 2(13.3%) isolates. Subculture Sorbitol-MacConkey agar revealed that 2 dumpsite EHEC O157:H7. Most resistant to Amoxicillin Augmentin (66.7% 73.3% respectively). One strains was found be Pefloxacin. Multidrug later became susceptible previously resisted antibiotics after plasmid curing using 10% sodium dodecyl sulphate (SDS). The outcome study suggests O157:H7 is not common in environment comparison other it associated dumpsites. Resistance plasmid-borne; therefore, indiscriminate use should avoided minimize rapid development bacterial strains. Dumping refuse close households also so as risk infection